Lead Scientist Cell Therapy

Job description

Are you a Cell Therapy Specialist with experience in GMP? This is your chance to be at the forefront of establishing a state-of-the-art development and production facility for the advancement of novel cell and gene therapies. We are looking for a Lead Scientist Cell Therapy with expertise in ex-vivo gene therapy to join our Cell Therapy Development team. 

What you will do 

While NECSTGEN was no more than a name just one year ago we now are in the process of realizing 13 cleanrooms and getting GMP certified by Q2 of 2022. In the meantime we will start our activities in a temporary development laboratory in Leiden Bio Science Park. NECSTGEN will provide expert knowledge for the development, production and commercialization of cell and gene therapies to customers at various stages of the therapy life cycle, in particular to academics and start-up companies. You as Lead Scientist Cell Therapy will: 

  • Support the set-up of the temporary development lab; 
  • Support the recruitment of a team and train future colleagues; 
  • Hands-on work in the lab and cleanroom to produce complex Cell Therapy Products;
  • Act as Subject Matter Expert in gene-therapy in cells (hence ex-vivo gene therapy products); 
  • Co-design and execute pathfinding process development projects (tech-transfer from R&D to GMP); 
  • Support the reviewing and writing of (GMP) protocols (for example SOPs).

Job requirements

What we ask

We are looking for an expert in ex-vivo gene therapy products who is able to act as a SME in work discussions and client meetings and worksd hands-on in the development lab and cleanroom. Furthermore you bring:  

  • A Masters or PhD degree in a relevant field; 
  • A minimum of 3 years experience in industry;
  • Experience with working with vectors and cells in a Good Manufacturing Process (GMP) environment, this is a must;
  • Experience with complex cell therapy products based on for example stem-cells, IPSCs, (CAR)T-cells, NK-cells or dendric cells; 
  • An open minded and spirited colleague who enjoys working in an ambitious collaborative team


Together with our clients and partners we challenge today’s possibilities to enable the unthinkable and make a difference in people’s lives by getting more cell and gene therapies to the patient.

The Netherlands Center for the Clinical advancement of Stem Cell and Gene Therapies (NECSTGEN) will primarily enable early-stage research organizations and start-ups to efficiently develop novel cell and gene therapies. Ultimately it is expected that NECSTGEN will engage with organisations of all scales worldwide. NESCTGEN is a spin out of the Leiden University Medical Center (LUMC) which is our only shareholder. This enables us to be not just a CDMO but a centre of expertise with a unique position. Our aim is to dedicate our resources to deliver high quality services, accessible to early stage research organizations and start-ups to develop novel cell and gene therapies. We recently signed a 15-year rental agreement to realize a facility of close to 4,000 m2 space including 13 cleanrooms for novel cell and gene therapy production.

NECSTGEN supports the translation of novel therapies and technologies to GMP production. We offer development and GMP manufacturing services, including fill and finish and bring together expertise from R&D, process development including analytical, Quality Assurance, Quality Control, Regulatory Affairs, Business Development and Manufacturing in a purpose-built GMP production facility.

Our current team consists of professionals from industry and academia with an entrepreneurial mind-set and a drive to make a difference. We are a flat organization with a participative management style. Visit our LinkedIn company page to learn more about our team and the latest developments.


As Lead Scientist Cell Therapy at NECSTGEN you will enjoy the best of both worlds; a competitive salary and excellent pension plan plus the opportunities and dynamics of a scale-up environment. A standard fulltime position at NECSTGEN is 36 hours, a part-time position is negotiable. In addition to your salary you receive a 13th-month payment and 8% holiday allowance.

Because As a Lead Scientist Cell Therapy you will join the team at an early stage giving you the unique opportunity to co-define the company and contribute to the establishment of NECSTGEN. All people joining the team now contribute expertise critical for the successful launch of NECSTGEN and hence you will enjoy a lot of responsibility and impact on key decisions.

If this position sparks your enthusiasm, we would love to hear from you! Don’t hesitate to contact Geertje Janssen at g.janssen@necstgen.com or +31(0) 6 15 93 34 54 for more information or send an message via LinkedIn. You will report to our Head of Cell Therapy, Melissa van Pel. First round interviews are scheduled for the second week of January 2021.